Bioceluloza / Biocellulose Bowil Biotech

Research & Development

At the R&D center, we create and develop new products, test new applications of biocellulose, and modify the material tailored to the customers’ needs. A creative team of experts and experienced professionals allows us to improve the technology and scientific research methodology, conduct theoretical analysis and systematic studies of our material.

Biocellulose is an excellent natural biomaterial with unique features that will find a special place on the biomedical market. Advanced manufacturing processes and technologies are the result of cooperation and exchange of experience with global experts. We are currently participating in scientific research projects on the application of biocellulose in reconstructive and regenerative medicine.


Under the Second Applied Research Program of the National Research and Development Center, with other scientific units, we co-develop a project based on conducting preclinical studies of the bioimplant applicability, used in cardiac and vascular surgery.

As a part of the consortium with the Medical University of Gdańsk, leading by the Head of project Piotr Siondalski, MD, PhD, we strived to develop a bacterial cellulose used as a biocompatible material for human cardiovascular system. The project was based on mechanical, biochemical, biostability and biocompatibility studies of biocellulose, in vitro and in vivo tests of vascular prostheses models, pericardial patch, pulmonary heart valve and aortic valve. The bioimplant is currently undergoing preclinical studies.


Participation in the project gave us the opportunity to business development by launching the Medical Research and Training Center. The program also aimed to demonstrate and popularize the unique healing properties and wide BC application among health professional and the local community.


As part of the project co-financed by the National Center for Research and Development, we conducted research on the development of biocellulose analgetic dressing for the treatment of patients after hemorrhoidectomy. For this purpose, we have established cooperation with physicians dealing with postoperative pain issue and commissioned research work to the Faculty of Pharmacy of the Medical University of Gdańsk.

Biocellulose has unique features that distinguish it from other materials used in cardiac surgery


densely woven nanofibers network holds > 95% of water


low immune response of material, coverage by healthy endothelium


atrombogenic surface, no hemolytic activity


superior sealing quality, impermeability to blood cells


high plasticity material, suture retention strength


free of pyrogens material


high durability, non-resorbable in vivo


calcification-resistant material, high fatigue strength


low prion transmission, no infectious agents from animals


hypoallergenic, biocompatible material


no cytotoxicity or genotoxic effects


excellent handling properties of biomaterial

Scientific materials

Wysunięcie In search of the ideal biomaterial Learn more

In search of the ideal biomaterial

Agata Humelt, PhD, Bowil Biotech Sp. z o.o.

The full white paper by clicking the link: In search of the ideal biomaterial

Wysunięcie Bacterial cellulose properties Learn more

Bacterial cellulose properties fulfilling requirements for a biomaterial of choice in reconstructive surgery and wound healing

J. Jankau, A. Błażyńska-Spychalska, K. Kubiak, M. Jędrzejczak-Krzepkowska, T. Pankiewicz, K. Ludwicka, A. Dettlaff, R. Pęksa

Wysunięcie Bionanocellulose composites Learn more

Bionanocellulose/poly(vinyl alcohol) composites produced by in-situ method and ex-situ impregnation or sterilization methods

A. Długa, J. Kowalonek, H. Kaczmarek

The full article by clicking the link: Materials (Basel), 14 (2021) 6340

Wysunięcie Assessment of the usefulness of bacterial cellulose Learn more

Assessment of the usefulness of bacterial cellulose produced by Gluconacetobacter xylinus E25 as a new biological implant

M. Kołaczkowska, P. Siondalski, M. M. Kowalik, R. Pęksa, A. Długa, W. Zając, P. Dederko, I. Kołodziejska, E. Malinowska-Pańczyk, I. Sinkiewicz, H. Staroszczyk, A. Śliwińska, A. Stanisławska, M. Szkodo, P. Pałczyńska, G. Jabłoński, A. Borman, P. Wilczek

The full article by clicking the link: Materials Science and Engineering C, 97 (2019) 302